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gloc-mikevs.csoyars

Bioinformatics - The Reverse Compliment

This will only work with TACG. Will accept lower cased values which are converted internally to upper case before replacement occurs and the compliment is returned.

Code
Diff
  • def reverse_compliment(dna):
    # ensure input is in upper case so replace works correctly
    uppercase_dna = dna.upper()
    # chain compliment replacements, convert to upper case & reverse return value
    return (
        uppercase_dna.replace("T", "a")
        .replace("A", "t")
        .replace("C", "g")
        .replace("G", "c")
        .upper()[::-1]
    )
    • def reverse_compliment(dna):
    • pass
    • # ensure input is in upper case so replace works correctly
    • uppercase_dna = dna.upper()
    • # chain compliment replacements, convert to upper case & reverse return value
    • return (
    • uppercase_dna.replace("T", "a")
    • .replace("A", "t")
    • .replace("C", "g")
    • .replace("G", "c")
    • .upper()[::-1]
    • )